11-Lean, also known as  and Adrenosterone, is a hormone produced by the adrenal gland and released in response to stress with other stress hormones like cortisol. Cortisol plays a vital role in maintaining homeostasis by increasing energy availability during times of stress by liberating fatty acids from fat tissues and increasing muscle protein breakdown to supply amino acids. Cortisol is needed by the body but elevated cortisol levels can lead to unwanted fat accumulation, excessive muscle breakdown, and symptoms of overtraining.

High cortisol levels can lead to the accumulation of visceral fat surrounding the organs, commonly referred to as a “beer belly.” Visceral fat can supply energy quickly to the liver during times of stress. Because visceral fat is more readily available to supply energy to the liver the body increases its storage in response to high cortisol levels because it thinks it needs more readily available energy to aid in the stress response. Chronically elevated cortisol levels leads to visceral fat storage.

In addition to increasing fat storage, high cortisol levels also increase the breakdown of muscle tissue. Cortisol decreases insulin sensitivity in the liver causing it to increase the formation of glucose through gluconeogenesis from amino acids obtained from muscle tissue. Chronically elevated cortisol levels leads to excessive muscle breakdown.

To make matters worse, high cortisol levels also reduces the secretion of TSH, LH, and GH from the pituitary gland, decreasing T3, testosterone, and IGF-I levels respectively. So not only does high cortisol levels increase body fat and decrease muscle mass it also decreases the levels of hormones needed to optimize fat loss and muscle gains. This is where 11-OXO comes into play.

11-lean(Adrenosterone) controls cortisol levels through selective inhibitor of 11b-hydroxysteroid dehydrogenase type I reductase (11HSD1R), the enzyme that converts cortisone to cortisol in the liver, muscle, and fat tissue. Costisone is basically an inactive form of cortisol, so by blocking 11HSD1R you decrease the body’s ability to convert cortisone to cortisol and thereby the total amount of cortisol in the body. By selectively inhibiting 11HSD1R--and not other enzymes--you can decrease the negative effects of cortisol while not suppressing it to the point where it cannot perform its positive actions in the body that are essential to overall health.

11-Lean Benefits

Selectively inhibiting 11HSD1R with 11-lean may lead to:

Increased fat loss (specifically visceral adipose tissue)

Improved insulin sensitivity

Increased muscle hardness

Optimal hormone production

COMPOSITION

Serving Size: 1
Servings Per Container: 90

Amount Per Serving:

11-lean (Adrenosterone)  125mg