S4
(Andarine)
(2S)-3-(4-acetamido-phenoxy)-2-hydroxy-2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-propionamide
S4
(Andarine) is an investigational selective androgen
receptor modulator (SARM) developed by GTX.INC for treatment of
conditions such
as muscle wasting, osteoporosis and benign prostatic hypertrophy, us
the
non-steroidal androgen antagonist bicalutamide as a lead compound.
Andarine
is an orally active partial agonist for
androgen receptors. In an animal model of benign prostatic hypertrophy,
andarine was shown to reduce prostate weight with similar efficacy to
finasteride, but without producing any reduction in muscle mass or
anti-androgenic side effects.This suggests that it is able to
competitively
block binding of dihydrostestosterone to its receptor targets in the
prostate
gland, but its partial agonist effects at androgen receptors prevent
the side
effects associated with the anti-androgenic drugs traditionally used
for
treatment of BPH.
Available Flavors:
not applicable (capsules)
1
caps. 2-3 times a day.
COMPOSITION
Serving
Size: 1
Servings Per Container: 90
Amount
Per Serving:
S4
(Andarine) 25mg